Mutator effects in Escherichia coli caused by the expression of specific foreign genes.

نویسندگان

  • Vanessa Gabrovsky
  • Mitsuko Lynn Yamamoto
  • Jeffrey H Miller
چکیده

Certain genes from Lactococcus lactis and Pseudomonas aeruginosa, including the nfxB gene, generate a mutator phenotype in Escherichia coli. The results of this study, together with those of a previous study, support conservation of regulatory sequences in E. coli and P. aeruginosa and suggest that some efflux pumps prevent mutagenicity by exporting mutagenic products of metabolism.

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عنوان ژورنال:
  • Journal of bacteriology

دوره 187 14  شماره 

صفحات  -

تاریخ انتشار 2005